Stem Cell Therapy for Alzheimer's Disease in a Preclinical Model Shows Potential Efficacy

Published 2023-08-10

In a study published in the August edition of Cell Reports, researchers from UC San Diego revealed data from a preclinical study utilizing Hematopoetic Stem Cells in an Alzheimer's Disease model. Mice that received healthy hematopoietic stem cells showed preserved memory and cognition, reduced neuroinflammation and significantly less β-amyloid build-up compared to other Alzheimer's mice. The benefit of the Stem Cell treatment was attributed to the impact on Microglia, immune cells in the brain. The ongoing inflammatory reaction of Microglia in Alzheimer's Disease is thought to one potential reason for disease progression.