Newly Discovered T-Cell May Provide New Tool for Cancer Immunotherapy
A team of researchers from Cardiff University led by Professor Andrea Sewell from the division of Infection and Immunity have discovered a new type of T-Cell with a unique marker conferring it the ability to recognize cancer cell's MR1 molecule. The research appears to show that targeting the MR1 molecule allows this type of T-Cell to specifically recognize and target cancer cells. Compared to conventional CAR-T immunotherapy approaches, utilizing this newly discovered T-Cell population may provide a more universal, yet cancer cell specific treatment approach. Preliminary studies in mice given a human immune system and human cancer cells appear to show significant benefit of this new approach. The study is published in the January 20th issue of Nature Immunology.
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