Dual Stem Cell Therapy Study

Published 2019-08-10

In a recent preclinical study published in Nature Communications, scientists from the City University of Hongkong utilized a combination of human bone marrow derived Mesenchymal Stem Cells (MSC) in combination with human Induced Pluripotent Stem Cells (iPSC) in a post Myocardial Infarction animal model. MSCs assumed the role of providing paracrine activity towards revascularization via a cardiac patch, while iPSCs provided the role of cardiomyocyte support via myocardial injection. The study demonstrated that MSCs improved iPSC survival and engraftment, while the combination of the two cell sources promoted significant cardiac regeneration.