Breakthrough Discovery Unveils Key Protein for Blood Stem Cell Regeneration

Published 2025-06-04

A recent breakthrough in stem cell science has unveiled a crucial molecular switch that governs blood stem cell regeneration. Researchers at Weill Cornell Medicine identified the DNA transcription-regulating protein FLI-1 as essential for activating blood stem cells from their dormant state to a regenerative one, enabling the production of new blood cells. This discovery, published in Nature Immunology, holds promise for enhancing bone marrow transplants and gene therapies by improving the mobilization and activation of stem cells, potentially leading to more effective treatments for blood disorders and related conditions