Needle Trauma and Stem Cell Survival

Published 2023-07-26

In a recent publication in the journal Nature, researchers from McLean Hospital and Massachusetts General Hospital addressed the limited survival of transplanted dopamine neuron cells in Parkinson's Disease models. The needle trauma generated by the injection procedure in the brain is thought to generate a local immune response which results in the death of the transplanted neurons. In this study, the addition of regulatory T-Cells to diminish the local immune response, resulted in a significantly higher survival of the transplanted neurons.